Squamous cells of undetermined significance ascus?
ASC-US (Atypical Squamous Cells of Undetermined Significance) Represents the most frequent situation of cytological abnormality. This term indicates the presence of squamous cells that have an atypical appearance, but of indeterminate meaning, that is, not referable with certainty to a specific disease.
Atypical Squamous Cells of Indeterminate Significance (ASC-US) means abnormal looking cells have been seen on your Pap smear. ... The cells in ASC-US are not cancerous cells.
ASCUS (Atypical Squamous Cells of Undetermined Significance) is a class of reporting of cervical cytological diagnoses. This diagnostic category was introduced in 1988 by the Bethesda System and has been further defined over the years.
ASCUS (Atypical Squamous cells of Undeterminated Significance) stands for Atypical Squamous Cells of Undetermined Meaning. It is an abbreviation used in Pap tests to indicate squamous cellular alterations that are difficult to interpret.
atypical is a word used by pathologists to describe cells that look abnormal when examined under a microscope. They are abnormal because they are different in shape, size or color than the normal, healthy cells usually found in that area of the body.
- In the woman, material is collected in the exo-endocervical area and / or in the external urinary meatus.
- In men, the sample is taken around the crown of the penis and in the external urinary meatus.
Squamous metaplasia is the conversion of a monostratified mucous and / or glandular epithelium to a multilayered squamous epithelium. Squamous metaplasia is not a tumor process; in fact, the cells of the epithelium involved maintain the characteristics of growth and replication typical of healthy cells.
To perform the colposcopy, the woman positions herself in the gynecological position and the gynecologist highlights the cervix using the vaginal speculum and applies reagent liquids (5% acetic acid and iodine-iodide solution) to differentiate the abnormal epithelium from the normal one.
If the Pap test is positive, the patient undergoes a second level examination, colposcopy, which allows, through a particular instrument and the use of specific colors, an enlarged view of the cervix and any lesions detected. with the screening test.
There is no pharmacological cure for internal lesions caused by the Papilloma virus, which can only be treated surgically, with laser vaporization in the mildest cases or with radiofrequency or conization of the uterine cervix if they are more extensive.
The epithelial cells (squamous and glandular) of the cervix present alterations of various degrees (specified below). These are suggestive but non-diagnostic abnormalities of HSIL (see below). For these anomalies further investigations are suggested.
The pap smear is the screening test for cervical cancer. It is used to determine the presence of abnormal or potentially abnormal cells in the vagina or cervix. In this way it is also possible to detect uterine infections due to bacteria, fungi and viruses.
Positive HPV test: in the cells taken from the patient's cervix, genetic material of the papilloma virus has been identified, suggesting an ongoing viral infection → the patient is considered at risk → need for cytological evaluation and any further diagnostic investigations.
The Pap test should be repeated every three / five years starting from the beginning of sexual activity or, in any case, from 20/25 years up to 65/70 to make the prevention effective and allow the doctor to identify lesions or cancer cells in the early stages.
- avoid sexual intercourse and use of creams, pessaries, douches or vaginal swabs in the 48 hours prior to the exam.
- bring with you on the day of the exam the results of the last Pap tests performed and the results of any previous colposcopies.
The first few days following colposcopy with biopsy could coincide with vaginal blood loss; as long as such bleeding is ongoing, it is advisable to refrain from sexual intercourse and from the use of vaginal drugs and creams, and to avoid undergoing vaginal tampons.
Colposcopy is indicated following a doubtful Pap smear. But if the exam schedule is respected, a possible lesion is identified in the pre-invasive phase. The Pap test is used to identify any possible alteration of the cervix, starting from a simple inflammation of the mucosa.
Currently, the causes of intestinal metaplasia are a mystery; however, doctors have observed that factors such as: Cigarette smoke have an effect on favoring the occurrence of the aforementioned phenomenon; Infections caused by Helicobacter Pylori, responsible for type B atrophic gastritis.
metaplasia: REVERSIBLE modification in which a differentiated cell type (epithelial or mesenchymal) is replaced by a different cell type. In other words, metaplasia is the CONVERSION OF ONE NORMAL TYPE OF ADULT CELL INTO ANOTHER TYPE OF NORMAL ADULT CELL.
The body is made up of many different types of specialized cells. Metaplasia describes a process in which a group of cells changes from one specialized cell type to a different specialized cell type.
THE HPV-DNA TEST IN AUXOLOGICAL
At the Auxologico Capitanio and Auxologico Pier Lombardo offices it is possible to carry out the HPV-DNA test by appointment. In all other Auxologico offices it is possible to carry out the HPV-DNA TEST without an appointment during the opening hours of the sampling points.
There is no real HPV test in humans so it is good practice to perform urethral, anal and oropharyngeal swabs where there are no visible lesions but there is a doubt or you are faced with risk situations such as partners with positive HPV, homosexuals (17% more to develop cancer of the anus), system ...
No, there is no direct relationship, HPV remains latent for a long time and can clinically manifest itself after many years with genital and / or extragenital lesions; discovering that you have it only means that you have contracted it at some point in your life. 4) "Do genital warts predispose to cancer?".
As the infection progresses and evolves into a tumor, typical symptoms such as discomfort or pain during sexual intercourse or blood loss after it rather than outside the menstrual period or after menopause, watery vaginal discharge sometimes foul-smelling, pain in area ...
In the absence of particular predispositions or risk factors (promiscuous sexual intercourse, smoking, AIDS ...), after the age of 21-25 the test should be repeated once every 3 years; after 30/35 years it can be replaced by the HPV DNA test, repeated once every 5 years in case of negative results.